Interactions of oral bacteria and osteoblasts

For successful integration of surgical implants into bone, new bone material must be produced by osteoblasts. Staphylococcus aureus is a major human pathogen, and can cause implant failure. Commensal streptococci are early colonizers of both the hard and soft tissues within the oral cavity and have...

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Bibliographic Details
Main Author: Moffatt, Catherine
Published: University of Bristol 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492464
Description
Summary:For successful integration of surgical implants into bone, new bone material must be produced by osteoblasts. Staphylococcus aureus is a major human pathogen, and can cause implant failure. Commensal streptococci are early colonizers of both the hard and soft tissues within the oral cavity and have the potential to influence oral implant outcome. This work investigated the interactions of Gram-positive bacteria with osteoblasts, comparing a known pathogen of bone, S. aureus, with the commensal organism S. gordonii.