Molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma
Topical photodynamic therapy (PDT) elicits a therapeutic response in both non melanoma skin cancer and immune-mediated skin disorders. Production of reactive oxygen species may result in direct cell death; however PDT-induced inflammatory and immune responses may also contribute to the therapeutic e...
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2008
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ndltd-bl.uk-oai-ethos.bl.uk-4934212017-12-24T16:32:19ZMolecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinomaEvangelou, Dr Georgios2008Topical photodynamic therapy (PDT) elicits a therapeutic response in both non melanoma skin cancer and immune-mediated skin disorders. Production of reactive oxygen species may result in direct cell death; however PDT-induced inflammatory and immune responses may also contribute to the therapeutic effects. The aims of my thesis were to examine for evidence of topical PDT-induced apoptosis and leucocyte trafficking, and the mechanisms underlying their mediation, in human skin.616.99477University of Manchesterhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493421Electronic Thesis or Dissertation |
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616.99477 Evangelou, Dr Georgios Molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma |
description |
Topical photodynamic therapy (PDT) elicits a therapeutic response in both non melanoma skin cancer and immune-mediated skin disorders. Production of reactive oxygen species may result in direct cell death; however PDT-induced inflammatory and immune responses may also contribute to the therapeutic effects. The aims of my thesis were to examine for evidence of topical PDT-induced apoptosis and leucocyte trafficking, and the mechanisms underlying their mediation, in human skin. |
author |
Evangelou, Dr Georgios |
author_facet |
Evangelou, Dr Georgios |
author_sort |
Evangelou, Dr Georgios |
title |
Molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma |
title_short |
Molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma |
title_full |
Molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma |
title_fullStr |
Molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma |
title_full_unstemmed |
Molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma |
title_sort |
molecular effects of topical photodynamic therapy in healthy human skin and basal cell carcinoma |
publisher |
University of Manchester |
publishDate |
2008 |
url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493421 |
work_keys_str_mv |
AT evangeloudrgeorgios moleculareffectsoftopicalphotodynamictherapyinhealthyhumanskinandbasalcellcarcinoma |
_version_ |
1718577686069116928 |