Transplantation of pancreatic islet in an immunoisolation device
Type-1 diabetes is caused by autoimmune destruction of insulin-producing β-cells in the pancreas. Today, transplantation of whole pancreas or islets is the only treatment that can restore endogenous insulin production. Within the past 20 years, pancreatic islet transplantation has become a clinical...
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Open University
2009
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ndltd-bl.uk-oai-ethos.bl.uk-4946292015-03-20T05:38:41ZTransplantation of pancreatic islet in an immunoisolation deviceCornolti, Roberta2009Type-1 diabetes is caused by autoimmune destruction of insulin-producing β-cells in the pancreas. Today, transplantation of whole pancreas or islets is the only treatment that can restore endogenous insulin production. Within the past 20 years, pancreatic islet transplantation has become a clinical reality and an option in diabetes treatment. However, large use of this therapy is limited by shortage in organ donations and use of immunosuppressive drugs. Immunoisolation potentially allows elimination of immuosuppressive drugs and use of xenogenic tissue solving the problem of a shortage in organ donation.616.46206Open Universityhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494629Electronic Thesis or Dissertation |
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616.46206 |
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616.46206 Cornolti, Roberta Transplantation of pancreatic islet in an immunoisolation device |
| description |
Type-1 diabetes is caused by autoimmune destruction of insulin-producing β-cells in the pancreas. Today, transplantation of whole pancreas or islets is the only treatment that can restore endogenous insulin production. Within the past 20 years, pancreatic islet transplantation has become a clinical reality and an option in diabetes treatment. However, large use of this therapy is limited by shortage in organ donations and use of immunosuppressive drugs. Immunoisolation potentially allows elimination of immuosuppressive drugs and use of xenogenic tissue solving the problem of a shortage in organ donation. |
| author |
Cornolti, Roberta |
| author_facet |
Cornolti, Roberta |
| author_sort |
Cornolti, Roberta |
| title |
Transplantation of pancreatic islet in an immunoisolation device |
| title_short |
Transplantation of pancreatic islet in an immunoisolation device |
| title_full |
Transplantation of pancreatic islet in an immunoisolation device |
| title_fullStr |
Transplantation of pancreatic islet in an immunoisolation device |
| title_full_unstemmed |
Transplantation of pancreatic islet in an immunoisolation device |
| title_sort |
transplantation of pancreatic islet in an immunoisolation device |
| publisher |
Open University |
| publishDate |
2009 |
| url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494629 |
| work_keys_str_mv |
AT cornoltiroberta transplantationofpancreaticisletinanimmunoisolationdevice |
| _version_ |
1716793295566274560 |