| Summary: | Many organisms utilise a co-translational signal recognition particle (SRP) system that interacts with ribosome-bound nascent polypeptides in a chaperone-like role. A novel post-translational chloroplast SRP (cpSRP) pathway has been discovered in higher plants. The cpSRP is unique as it includes a 43 kDa protein, cpSRP43, and does not require an RNA component. Together with cpSRP54, and cpFtsY, the cpSRP forms a protein routing pathway that transports protein through the aqueous phase of the chloroplast stroma to the thylakoid membrane. Once at the membrane an insertase, Alb3, is involved in correct insertion of transported proteins into the membrane.
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