Regulation of viral gene expression during infection with enteric viruses
In this study two enteric viruses, poliovirus and adenovirus type 40, were used to investigate virus - host cell interactions in the gastrointestinal environment. Human enteric adenoviruses have been previously shown to be sensitive to IFN-treatment of cells and a STAT-deficient cell line allows imp...
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University of Nottingham
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495601 |
| Summary: | In this study two enteric viruses, poliovirus and adenovirus type 40, were used to investigate virus - host cell interactions in the gastrointestinal environment. Human enteric adenoviruses have been previously shown to be sensitive to IFN-treatment of cells and a STAT-deficient cell line allows improved growth of enteric adenovirus type 40. Two adenoviral gene products, the virus-associated RNA (VA RNA) and the El A, have been previously shown to be responsible for viral countermeasures against IFN actions in the host cell. |
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