Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours

Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours

Resistance to chemotherapy has been reported in various malignancies and constitutes a major challenge in cancer care. Over the years, several pathways have been suggested in the literature, but the mechanisms behind resistance to treatment remain unclear. Testicular germ cell tumours (TGCTs), the m...

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Main Author: Noel, Elodie Emilie
Published: Queen Mary, University of London 2008
Subjects:
616.994
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497922
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spelling ndltd-bl.uk-oai-ethos.bl.uk-4979222015-03-20T06:11:51ZGenetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumoursNoel, Elodie Emilie2008Resistance to chemotherapy has been reported in various malignancies and constitutes a major challenge in cancer care. Over the years, several pathways have been suggested in the literature, but the mechanisms behind resistance to treatment remain unclear. Testicular germ cell tumours (TGCTs), the most common malignancy in young men, are known for their extreme sensitivity to cisplatin-based chemotherapy and their excellent clinical outcome, making them an ideal tumour model for the investigation of cisplatin-induced sensitivity and resistance.616.994Queen Mary, University of Londonhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497922Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 616.994
spellingShingle 616.994
Noel, Elodie Emilie
Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours
description Resistance to chemotherapy has been reported in various malignancies and constitutes a major challenge in cancer care. Over the years, several pathways have been suggested in the literature, but the mechanisms behind resistance to treatment remain unclear. Testicular germ cell tumours (TGCTs), the most common malignancy in young men, are known for their extreme sensitivity to cisplatin-based chemotherapy and their excellent clinical outcome, making them an ideal tumour model for the investigation of cisplatin-induced sensitivity and resistance.
author Noel, Elodie Emilie
author_facet Noel, Elodie Emilie
author_sort Noel, Elodie Emilie
title Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours
title_short Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours
title_full Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours
title_fullStr Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours
title_full_unstemmed Genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours
title_sort genetic investigation of the mechanisms of chemo-resistance in testicular germ cell tumours
publisher Queen Mary, University of London
publishDate 2008
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497922
work_keys_str_mv AT noelelodieemilie geneticinvestigationofthemechanismsofchemoresistanceintesticulargermcelltumours
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