Efficacy and safety of paediatric immunization-linked intermittent preventive treatment in infants (IPTi) in the prevention of malaria morbidity in rural western Kenya
Background: Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) for the prevention of malaria has shown encouraging results in recent trials. However, resistance to SP is rising and alternative drugs for IPTi need to be evaluated. Objectives: To evaluate the safe...
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University of Liverpool
2008
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501591 |
Summary: | Background: Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) for the prevention of malaria has shown encouraging results in recent trials. However, resistance to SP is rising and alternative drugs for IPTi need to be evaluated. Objectives: To evaluate the safety and efficacy of different drugs for IPTi and to better understand the role of treatment vs. prophylactic effect of IPTi by comparing short and long-acting antimalarials. |
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