Humanised recombinant antibodies for human cancer therapy

Humanised recombinant antibodies for human cancer therapy

Humanisation of rodent mAbs by CDR-grafting is now a standard procedure for reducing immunogenicity and recruiting human effector functions with ten humanised mAbs approved for use and many more in development. This project aimed to develop two anti-cancer therapeutics aimed at exploiting two tumour...

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Main Author: Davidson, Lisa
Published: University of Strathclyde 2009
Subjects:
616.99406
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501643
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spelling ndltd-bl.uk-oai-ethos.bl.uk-5016432015-03-20T05:31:02ZHumanised recombinant antibodies for human cancer therapyDavidson, Lisa2009Humanisation of rodent mAbs by CDR-grafting is now a standard procedure for reducing immunogenicity and recruiting human effector functions with ten humanised mAbs approved for use and many more in development. This project aimed to develop two anti-cancer therapeutics aimed at exploiting two tumour associated antigens overexpressed in the tumour environment.616.99406University of Strathclydehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501643Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 616.99406
spellingShingle 616.99406
Davidson, Lisa
Humanised recombinant antibodies for human cancer therapy
description Humanisation of rodent mAbs by CDR-grafting is now a standard procedure for reducing immunogenicity and recruiting human effector functions with ten humanised mAbs approved for use and many more in development. This project aimed to develop two anti-cancer therapeutics aimed at exploiting two tumour associated antigens overexpressed in the tumour environment.
author Davidson, Lisa
author_facet Davidson, Lisa
author_sort Davidson, Lisa
title Humanised recombinant antibodies for human cancer therapy
title_short Humanised recombinant antibodies for human cancer therapy
title_full Humanised recombinant antibodies for human cancer therapy
title_fullStr Humanised recombinant antibodies for human cancer therapy
title_full_unstemmed Humanised recombinant antibodies for human cancer therapy
title_sort humanised recombinant antibodies for human cancer therapy
publisher University of Strathclyde
publishDate 2009
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501643
work_keys_str_mv AT davidsonlisa humanisedrecombinantantibodiesforhumancancertherapy
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