The regulation of plasminogen activator inhibitor-l(PAI-l) and other uPA system members in the gastricepithelium by Helicobacter pylori

The gastric pathogen Helicobacter pylori is linked to gastritis, leading to gastric cancer but the mechanisms are unclear. Gastritis is characterised by remodelling of the gastric mucosa, which requires degradation of the extracellular matrix (ECM). Proteases such as matrix metalloproteinases (MMPs)...

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Bibliographic Details
Main Author: Kenny, Susan Helen
Published: University of Liverpool 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502254