Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins

Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins

RNA polymerase III (pol III) is responsible for transcribing a set of genes that are involved in protein synthesis, including transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Pol III transcription levels are increased in many cancers, as increased protein synthesis is required for tumour growth. Furt...

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Bibliographic Details
Main Author: Spandidos, Nikiforos
Published: University of Glasgow 2010
Subjects:
572.8
Q Science (General)
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512143
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spelling ndltd-bl.uk-oai-ethos.bl.uk-5121432015-09-03T03:15:22ZRegulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteinsSpandidos, Nikiforos2010RNA polymerase III (pol III) is responsible for transcribing a set of genes that are involved in protein synthesis, including transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Pol III transcription levels are increased in many cancers, as increased protein synthesis is required for tumour growth. Furthermore, it has been shown that a number of oncoproteins and tumour suppressor proteins interact directly with the pol III machinery. The work presented in this thesis aimed to investigate whether the inhibitor of differentiation (ID) and E47 proteins regulate pol III transcription, as well as the mechanisms behind these processes.572.8Q Science (General)University of Glasgowhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512143http://theses.gla.ac.uk/1723/Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 572.8
Q Science (General)
spellingShingle 572.8
Q Science (General)
Spandidos, Nikiforos
Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
description RNA polymerase III (pol III) is responsible for transcribing a set of genes that are involved in protein synthesis, including transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Pol III transcription levels are increased in many cancers, as increased protein synthesis is required for tumour growth. Furthermore, it has been shown that a number of oncoproteins and tumour suppressor proteins interact directly with the pol III machinery. The work presented in this thesis aimed to investigate whether the inhibitor of differentiation (ID) and E47 proteins regulate pol III transcription, as well as the mechanisms behind these processes.
author Spandidos, Nikiforos
author_facet Spandidos, Nikiforos
author_sort Spandidos, Nikiforos
title Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
title_short Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
title_full Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
title_fullStr Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
title_full_unstemmed Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
title_sort regulation of rna polymerase iii transcription by the id1, id2, id3 and e47 proteins
publisher University of Glasgow
publishDate 2010
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512143
work_keys_str_mv AT spandidosnikiforos regulationofrnapolymeraseiiitranscriptionbytheid1id2id3ande47proteins
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