A Bayesian cost-benefit approach to sample size determination and evaluation in clinical trials
Current practice for sample size computations in clinical trials is largely based on frequentist or classical methods. These methods have the drawback of requiring a point estimate of the variance of treatment effect and are based on arbitrary settings of type I and II errors. They also do not direc...
Main Author: | Kikuchi, Takashi |
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Other Authors: | Gittins, John |
Published: |
University of Oxford
2011
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540251 |
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