Disulfide-bridging PEGylation of antibody fragments

Monoclonal antibodies are routinely used in the clinic. There is also a small number of antibody fragments (e.g. Fabs) that are clinically used. In many applications where antibody binding is required to antagonise a receptor or simply to bind a ligand, there is no need for the Fe properties that ar...

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Bibliographic Details
Main Author: Khalili, Hanieh
Published: University College London (University of London) 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553694