Growth factor interactions with platelet-derived growth factor receptor alpha

The interaction between a growth factor and the extracellular region of its receptor is the first step in triggering the intracellular signalling pathways that induce a change in cell phenotype. Several platelet-derived growth factors (PDGFs) each bind to and activate PDGF receptor (PDGFR) alpha, a...

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Bibliographic Details
Main Author: Bayley, Christopher
Other Authors: Kielty, Catherine
Published: University of Manchester 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554156