Functional selectivity and desensitisation of G protein-coupled receptors
The existence of functional selectivity at the mu-opioid receptor was examined by determining the efficacy of a range of opioid agonists for promoting G protein activation and arrestin-3 translocation. In general, there is a good correlation between the efficacy of an opioid agonist at promoting G p...
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University of Bristol
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555868 |