Elucidating the expression pattern and role of the oncogenic GLI transcription factors in basal cell carcinoma
Basal Cell Carcinoma (BCC) is the most common type of skin cancer; its development is associated with mutational inactivation of the PTCH1 tumour suppressor gene leading to deregulation of the Hedgehog pathway through increased expression of the downstream GLI (GLI1 and GLI2) transcription factors....
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Queen Mary, University of London
2012
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Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564464 |