Behavioural analysis of transgenic mice overexpressing gamma-synuclein
The alpha-synucleinopathies is a diverse group of diseases characterised by malfunctioning of alpha-synuclein protein. Parkinson’s disease is the most common of all alpha-synucleinopathies. Intracellular inclusions, like Lewy bodies and certain other abnormal structures are the pathological hallmark...
| Main Author: | |
|---|---|
| Published: |
Cardiff University
2011
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567241 |
| id |
ndltd-bl.uk-oai-ethos.bl.uk-567241 |
|---|---|
| record_format |
oai_dc |
| spelling |
ndltd-bl.uk-oai-ethos.bl.uk-5672412015-03-20T03:23:28ZBehavioural analysis of transgenic mice overexpressing gamma-synucleinSalem, Hatem2011The alpha-synucleinopathies is a diverse group of diseases characterised by malfunctioning of alpha-synuclein protein. Parkinson’s disease is the most common of all alpha-synucleinopathies. Intracellular inclusions, like Lewy bodies and certain other abnormal structures are the pathological hallmarks of this group of neurodegenerative diseases. The main protein component of these structures is alpha-synuclien. Alpha-synuclein is a member of the synuclein family, which consists of 3 closely related proteins, alpha-, beta- and gamma-synucleins. Alpha-synuclein is more extensively studied because of its direct involvement in human diseases, while our knowledge about two other family members is very limited. Neither beta-synuclein, nor gamma-synuclein is a component of Lewy bodies and other pathological structures typical for neurodegenerative diseases.616.8QH301 BiologyCardiff Universityhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567241http://orca.cf.ac.uk/32398/Electronic Thesis or Dissertation |
| collection |
NDLTD |
| sources |
NDLTD |
| topic |
616.8 QH301 Biology |
| spellingShingle |
616.8 QH301 Biology Salem, Hatem Behavioural analysis of transgenic mice overexpressing gamma-synuclein |
| description |
The alpha-synucleinopathies is a diverse group of diseases characterised by malfunctioning of alpha-synuclein protein. Parkinson’s disease is the most common of all alpha-synucleinopathies. Intracellular inclusions, like Lewy bodies and certain other abnormal structures are the pathological hallmarks of this group of neurodegenerative diseases. The main protein component of these structures is alpha-synuclien. Alpha-synuclein is a member of the synuclein family, which consists of 3 closely related proteins, alpha-, beta- and gamma-synucleins. Alpha-synuclein is more extensively studied because of its direct involvement in human diseases, while our knowledge about two other family members is very limited. Neither beta-synuclein, nor gamma-synuclein is a component of Lewy bodies and other pathological structures typical for neurodegenerative diseases. |
| author |
Salem, Hatem |
| author_facet |
Salem, Hatem |
| author_sort |
Salem, Hatem |
| title |
Behavioural analysis of transgenic mice overexpressing gamma-synuclein |
| title_short |
Behavioural analysis of transgenic mice overexpressing gamma-synuclein |
| title_full |
Behavioural analysis of transgenic mice overexpressing gamma-synuclein |
| title_fullStr |
Behavioural analysis of transgenic mice overexpressing gamma-synuclein |
| title_full_unstemmed |
Behavioural analysis of transgenic mice overexpressing gamma-synuclein |
| title_sort |
behavioural analysis of transgenic mice overexpressing gamma-synuclein |
| publisher |
Cardiff University |
| publishDate |
2011 |
| url |
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567241 |
| work_keys_str_mv |
AT salemhatem behaviouralanalysisoftransgenicmiceoverexpressinggammasynuclein |
| _version_ |
1716780552177057792 |