Role of oestrogen receptor phosphorylation in the growth of endocrine-responsive and anti-oestrogen-resistant breast cancer cell lines
EGFR/MAPK signalling has been implicated in mediating tamoxifen-resistant breast cancer cell growth in the clinic and in preclinical models. However, ERa expression and functionality has also been shown to be maintained in this condition. ERa transcriptional activity can be driven, in a tigand-indep...
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Cardiff University
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.583518 |