Investigation of the influence of CD4+CD25+ regulatory cells on the generation of tumour immunity in mice and human patients
A population of T cells identified as CD4+CD25+FOXP3+ (Tregs) are present in rodents and humans. These cells are vital for suppressing the activity of conventional self- reactive T cells. Previous work conducted using tumour cell lines has indicated that Tregs also suppress effective anti-tumour imm...
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Cardiff University
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.584180 |