Mechanisms of action of rosiglitazone in the protection of pancreatic beta cells from free fatty acid induced damage
A wealth of recent evidence implicates increasing obesity levels in the rising global epidemic of type 2 diabetes. At a cellular level, high fatty acid concentrations contribute to increasing p-cell dysfunction and eventual p-cell failure. We have shown that the thiazolidinedione (TZD) rosiglitazone...
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University of Brighton
2011
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590004 |