Chemical and biological studies with Nek2 kinase inhibitors
The aim of modern cancer chemotherapy is to develop targeted drugs designed to exploit pharmacological differences between tumour cells and healthy tissues. One focus of this effort has been the identification of protein kinases that are expressed at elevated levels or in mutated forms, indicating a...
Main Author: | Matheson, Christopher |
---|---|
Published: |
University of Newcastle upon Tyne
2012
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594499 |
Similar Items
-
Design and synthesis of purine isosteres as inhibitors of Nek2 and CDK2
by: Turner, David Michael
Published: (2013) -
Validating the Nima-related kinase Nek2 as a novel chemotherapeutic target
by: Hayward, Daniel
Published: (2007) -
Characterization of the conformational dynamics of the Nek2 leucine zipper domain
by: Croasdale, Rebecca Alice
Published: (2013) -
An evaluation of the checkpoint kinase inhibitor V158411
by: Stephens, Peter Andrew
Published: (2015) -
The response of cancer cells to mitotic kinase inhibitors
by: Aspinall, Claire
Published: (2013)