B cells as antigen-presenting cells in a model of rheumatoid arthritis

Rheumatoid arthritis (RA) is a multifaceted inflammatory autoimmune disease characterised by the infiltration of leukocytes into synovial joints leading to the destruction of articular cartilage and bone. Autoreactive CD4+ T cells producing inflammatory cytokines are implicated in disease pathogenes...

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Bibliographic Details
Main Author: Hine, Dominic William
Published: University of Newcastle upon Tyne 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.594564