The total synthesis of the bicyclic acetal core of zaragozic acid C

Zaragozic acid C 33 is a member of a family of naturally occurring, structurally complex fungal metabolites. These natural products are potent inhibitors of the enzyme squalene synthetase. All the zaragozic acids show a common, highly oxygenated 2,8-dioxobicyclo[3.2.1]octane "core" unit an...

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Bibliographic Details
Main Author: Finlay, M. R. V.
Published: University of Cambridge 1997
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599027

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