Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates

The synthesis of β-silylated carbonyl compounds and their use as masked αβ-unsaturated carbonyl compounds is described. The β-silylated function in these molecules is stable to most reaction conditions, yet the introduction of a leaving group in the α-position and reaction with a suitable nucleophil...

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Bibliographic Details
Main Author:	Goldhill, Jonathan Paul
Published:	University of Cambridge 1979
Subjects:	546.3
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599474

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spelling	ndltd-bl.uk-oai-ethos.bl.uk-5994742015-03-20T05:59:19ZSilicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolatesGoldhill, Jonathan Paul1979The synthesis of β-silylated carbonyl compounds and their use as masked αβ-unsaturated carbonyl compounds is described. The β-silylated function in these molecules is stable to most reaction conditions, yet the introduction of a leaving group in the α-position and reaction with a suitable nucleophile for silicon gives an α-methylene carbonyl. The reactions of O-silylated dienolates with a range of electrophiles were investigated and shown to provide a partial solution to the problem of the γ-alkylation of αβ-unsaturated carbonyl compounds.546.3University of Cambridgehttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599474Electronic Thesis or Dissertation
collection	NDLTD
sources	NDLTD
topic	546.3
spellingShingle	546.3 Goldhill, Jonathan Paul Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates
description	The synthesis of β-silylated carbonyl compounds and their use as masked αβ-unsaturated carbonyl compounds is described. The β-silylated function in these molecules is stable to most reaction conditions, yet the introduction of a leaving group in the α-position and reaction with a suitable nucleophile for silicon gives an α-methylene carbonyl. The reactions of O-silylated dienolates with a range of electrophiles were investigated and shown to provide a partial solution to the problem of the γ-alkylation of αβ-unsaturated carbonyl compounds.
author	Goldhill, Jonathan Paul
author_facet	Goldhill, Jonathan Paul
author_sort	Goldhill, Jonathan Paul
title	Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates
title_short	Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates
title_full	Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates
title_fullStr	Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates
title_full_unstemmed	Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates
title_sort	silicon in synthesis : β-silylated carbonyl compounds and o-silylated dienolates
publisher	University of Cambridge
publishDate	1979
url	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599474
work_keys_str_mv	AT goldhilljonathanpaul siliconinsynthesisbsilylatedcarbonylcompoundsandosilylateddienolates
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Silicon in synthesis : β-silylated carbonyl compounds and O-silylated dienolates

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