Investigation into ubiquitin signalling in response to cisplatin

Cisplatin is an anti-cancer drug that acts by introducing toxic DNA interstrand crosslinks into proliferating cells, causing both cytostatic and cytotoxic effects. Although various models of the interstrand crosslink (ICL) response have been proposed, none of them are complete and much still remains...

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Bibliographic Details
Main Author: Carroll, Eilis
Published: University of Dundee 2014
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613613