Validation of phosphodiesterase isozymes as targets for pulmonary hypertension
Pulmonary hypertension (PH) is a debilitating disease with a very poor prognosis. Increasing lung cyclic GMP (cGMP) levels is clinically effective in treating the disease, but since many endogenous pathways regulate cGMP synthesis and metabolism, there exists considerable scope for further optimisin...
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University College London (University of London)
2013
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626232 |