Multiple dopamine signalling pathways antagonize RHO-1 signalling in the nervous system
Alterations in RhoA (RHO-1) signalling cause neuronal signalling defects in both mammals and C. elegans. In the case of C. elegans, exaggerated RHO-1 signalling in cholinergic neurons (nRHO-1*) has numerous effects that include increased release of acetylcholine (ACh) and exaggerated body curvature...
Main Author: | |
---|---|
Published: |
University College London (University of London)
2014
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626805 |