Validation of HDAC6 and SIRT2 tubulin deacetylases as therapeutic targets for Huntington's disease

Validation of HDAC6 and SIRT2 tubulin deacetylases as therapeutic targets for Huntington's disease

Since the identification of a widespread transcriptional dysregulation that occurs in Huntington's disease (HD), histone deacetylase (HDAC) inhibition has been explored as a possible therapeutic strategy for this devastating disease. Studies using broadrange acting HDAC inhibitors have shown gr...

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Bibliographic Details
Main Author:	Bobrowska, Anna
Published:	King's College London (University of London) 2012
Subjects:	616.85
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628114

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