An investigation of the artificial chromosome expression system for production of recombinant proteins

The requirement to produce complex, therapeutic proteins that possess human-like post-translational modifications for treatment of disease has accelerated the use of mammalian cell lines, in particular Chinese hamster ovary (CHO) cells, in the biopharmaceutical industry. However, producing stable, h...

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Bibliographic Details
Main Author: Cirmirakis, A. K.
Published: University College London (University of London) 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.632094