A novel linker and its application for carbohydrate chemistry on the solid phase
The novel <i>exo</i>-enzyme cleavable linker <i>N</i>-1-(4-(3-aminopropylcarbamoyl)-phenyl)ethylsulfanyl)-methyl)-1-phenylacetamide (1) was successfully synthesised and its potential for use in solid phase carbohydrate chemistry was investigated. Sugar substrates were synthes...
Main Author: | |
---|---|
Published: |
University of Edinburgh
2000
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.642231 |
Summary: | The novel <i>exo</i>-enzyme cleavable linker <i>N</i>-1-(4-(3-aminopropylcarbamoyl)-phenyl)ethylsulfanyl)-methyl)-1-phenylacetamide (1) was successfully synthesised and its potential for use in solid phase carbohydrate chemistry was investigated. Sugar substrates were synthesised in solution and attached to solid support <i>via exo</i>-linker 1, which is also cleavable under mildly acidic conditions. (Fig. 9963) |
---|