The genetic modification of enzymes towards an anti-cancer prodrug activation system

Cancer is the most common cause of death worldwide and therefore attracts significant research attention. Directed enzyme-pro drug therapy offers a selective approach which can kill tumour cells whilst limiting the damage to healthy cells. Nitroreductases have potential applications in enzyme/prodru...

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Bibliographic Details
Main Author: Mohmmad Kareem, Shokrea Ali
Published: Bangor University 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664600