An analysis of intrinsically disordered proteins using hidden Markov models and experimental design of stochastic kinetic models

An intrinsically disordered protein (IDP) is a protein without a stable secondary or tertiary structure and just over one third of human proteins can be described as IDPs. There has been shown to be a link between neurodegenerative diseases, cancer and protein misfolding, with many of these misfolde...

Full description

Bibliographic Details
Main Author: Wilkinson, Nina
Published: University of Newcastle upon Tyne 2015
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680316