Phytochemical and biological investigation of Erigeron annuus (L.) Pers for antimicrobial activity and potential DNA gyrase inhibitors

Compositae plants of the genus Erigeron have ca. 390 species, widely distributed in most temperate regions around the world. Erigeron anl7UUS (L.) Pers. (fleabane) is one of the most valuable plants in this genus, used in Chinese foll< medicine to treat indigestion, malaria, enteritis, hepatitis...

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Bibliographic Details
Main Author: Zhang, Yi Fan
Published: London Metropolitan University 2014
Subjects:
583
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.681021
Description
Summary:Compositae plants of the genus Erigeron have ca. 390 species, widely distributed in most temperate regions around the world. Erigeron anl7UUS (L.) Pers. (fleabane) is one of the most valuable plants in this genus, used in Chinese foll< medicine to treat indigestion, malaria, enteritis, hepatitis and hematuria increasingly since the 1970s. However, it is not an indigenous species in China and has not been officially recorded in the Chinese Pharmacopeia. Very little research has been published on its biological activity and no activity against MRSA has been reported . In this research, whole plant material was collected in Shanghai, China and its chemical composition , antibacterial activity, DNA gyrase inhibitory activity and mutagenicity assessment were evaluated on isolated compounds and extracts.