Novel routes towards securing human osteoblast maturation for potential orthopaedic applications

Novel routes towards securing human osteoblast maturation for potential orthopaedic applications

Osteoarthritis is a common condition that affects many men and women globally. The mainstay of treatment is joint replacement, or arthroplasty, however roughly 10% of arthroplasty operations performed in the UK will require revision for 'aseptic loosening', which refers to loosening betwee...

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Main Author: Lancaster, Sarah Tamar
Published: University of Bristol 2014
Subjects:
616.7
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685356
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spelling ndltd-bl.uk-oai-ethos.bl.uk-6853562017-03-16T16:23:31ZNovel routes towards securing human osteoblast maturation for potential orthopaedic applicationsLancaster, Sarah Tamar2014Osteoarthritis is a common condition that affects many men and women globally. The mainstay of treatment is joint replacement, or arthroplasty, however roughly 10% of arthroplasty operations performed in the UK will require revision for 'aseptic loosening', which refers to loosening between the prosthesis and host bone. During revision procedures, it is possible that bone will be lost, for example from the acetabulum during hip arthroplasty revision. There are also some cases, for example fracture non-union or fusion operations, where bone is lost. Therefore a mechanism by which bone repair regeneration may be enhanced has the potential to have widespread applications in orthopaedic surgery.616.7University of Bristolhttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685356Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 616.7
spellingShingle 616.7
Lancaster, Sarah Tamar
Novel routes towards securing human osteoblast maturation for potential orthopaedic applications
description Osteoarthritis is a common condition that affects many men and women globally. The mainstay of treatment is joint replacement, or arthroplasty, however roughly 10% of arthroplasty operations performed in the UK will require revision for 'aseptic loosening', which refers to loosening between the prosthesis and host bone. During revision procedures, it is possible that bone will be lost, for example from the acetabulum during hip arthroplasty revision. There are also some cases, for example fracture non-union or fusion operations, where bone is lost. Therefore a mechanism by which bone repair regeneration may be enhanced has the potential to have widespread applications in orthopaedic surgery.
author Lancaster, Sarah Tamar
author_facet Lancaster, Sarah Tamar
author_sort Lancaster, Sarah Tamar
title Novel routes towards securing human osteoblast maturation for potential orthopaedic applications
title_short Novel routes towards securing human osteoblast maturation for potential orthopaedic applications
title_full Novel routes towards securing human osteoblast maturation for potential orthopaedic applications
title_fullStr Novel routes towards securing human osteoblast maturation for potential orthopaedic applications
title_full_unstemmed Novel routes towards securing human osteoblast maturation for potential orthopaedic applications
title_sort novel routes towards securing human osteoblast maturation for potential orthopaedic applications
publisher University of Bristol
publishDate 2014
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.685356
work_keys_str_mv AT lancastersarahtamar novelroutestowardssecuringhumanosteoblastmaturationforpotentialorthopaedicapplications
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