Crystal structure of the vinculin tail domain and a model for activation

Basic physical mechanisms underlying the regulation of focal adhesion formation and function include aggregation, phosphorylation and conformational changes of the molecules involved. Vinculin is a protein located at sites of cell-cell and cell-matrix adhesion where it plays a dynamic role in the as...

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Bibliographic Details
Main Author: Bakolitsa, Constantina
Published: University of Leicester 1999
Subjects:
612
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696580

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