Regulation of tylosin production in Streptomyces fradiae

The tylosin biosynthetic (tyl) gene cluster of S. fradiae contains at least five regulatory genes (tylP, Q, R, S, T). During promoter-probe analysis, TylP inhibited expression from tylPp in S. lividans, raising the possibility of autoregulation. TylP also negatively regulated the expression of tylQ...

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Bibliographic Details
Main Author: Stratigopoulos, George
Published: University of Leicester 2002
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697085