Kinetochore dynamics and their attachment to the mitotic spindle

Chromosome segregation is a mechanical process that requires assembly of the mitotic spindle – a dynamic microtubule-based force-generating machine (Dumont & Mitchison, 2009). Connections between chromosomes and the spindle are mediated by kinetochores, pairs of multi-protein complexes assembled...

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Bibliographic Details
Main Author: Smith, Christopher
Published: University of Warwick 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.698765