Investigations into the structure, function and pharmacology of TREK K2P potassium channels

TREK channels are polymodal potassium channels which act as integrators of diverse chemical and physical stimuli to dynamically control the cellular membrane potential. How the channels sense different stimuli, and how this is transduced to channel gating is not fully understood. Here I report the r...

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Bibliographic Details
Main Author: McClenaghan, Conor
Other Authors: Tucker, Stephen J. ; Ashcroft, Frances M.
Published: University of Oxford 2015
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712465