Computational modelling of activation mechanisms in ligand-gated ion channels

Pentameric ligand-gated ion channels (pLGICs) are a family of membrane proteins that mediate the fast synaptic communication between neurons. The delicate role played by these neuroreceptors makes them major therapeutic targets for a variety of neuronal disorders, including Alzheimer's disease,...

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Bibliographic Details
Main Author: Comitani, Federico
Other Authors: Lorenz, Christian ; Molteni, Carla
Published: King's College London (University of London) 2017
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713103

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