Investigation of phenotypic rescue of Mybpc3 deficient mouse

Investigation of phenotypic rescue of Mybpc3 deficient mouse

Mutations in the myosin binding protein C gene (MYBPC3) are a frequent cause of hypertrophic cardiomyopathy (HCM) and calcineurin plays a major role in hypertrophic remodelling. However, a functional link between MYBPC3 mutations and calcineurin has not been investigated. Mybpc3 knock out (KO) mice...

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Bibliographic Details
Main Author:	Abou Al Saud, Sara
Other Authors:	Marston, Steven ; Knoell, Ralph ; Ferenczi, Mike
Published:	Imperial College London 2015
Subjects:	572
Online Access:	https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718387

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