Interrogation of Rab8 as a therapeutic target for Huntington's disease in Drosophila melanogaster
Huntington’s disease (HD) is a familial neurodegenerative disorder largely caused by atrophy in the striatal and cortical regions of the brain. At the molecular level HD is triggered by a trinucleotide CAG repeat expansion in the Huntingtin gene (HTT), which encodes a poly glutamine (polyQ) stretch,...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Leicester
2017
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718724 |