A scale-down evaluation of adsorptive process options for the recovery and initial purification of antibody fragments from crude E. coli feedstocks
Improvements in fermentation processes, coupled with the rising demand for biologies, are requiring that new ways in which therapeutics are recovered and purified be identified. Column-based approaches are constrained by the need for pre-treatment which leads to decreases in process yield and throug...
Main Author: | Ujam, S. B. |
---|---|
Published: |
University College London (University of London)
2007
|
Subjects: | |
Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719069 |
Similar Items
-
Characterisation of a biosensor surface for use with scale-down technologies in the process monitoring of Escherichia coli antibody fragment production
by: Perez Pardo, M. A.
Published: (2014) -
Design and characterisation of a scale-down platform for the recovery of periplasmic Fab' from E. coli
by: Ahmad, Asma
Published: (2018) -
Scale down mimics for viral vaccine harvest and early purification
by: Melinek, Beatrice
Published: (2018) -
Stability, structure, and formulation of antibody fragments during bioprocessing
by: Uye, U. O.
Published: (2014) -
Elucidating the aggregation mechanisms of antibody fragments through biophysical analysis
by: Hilton, D. W.
Published: (2016)