Personalised medicine in rectal cancer : understanding and predicting response to neoadjuvant chemoradiotherapy

Around 12-15% of patients with locally advanced rectal cancer (LARC) undergo a pathologically complete response (Tumour Regression Grade 4 - TRG4) to neoadjuvant chemoradiotherapy; the remainder exhibit a spectrum of tumour regression (TRG1-3). Understanding therapy-related genomic alterations may h...

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Bibliographic Details
Main Author: Alderdice, Matthew
Published: Queen's University Belfast 2017
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725327