Evidence of dynamics and disorder using NMR-spectroscopic techniques applied to human Flap-Endonuclease-1
Flap endonuclease 1 (FEN1) is a member of a 5’ nuclease superfamily involved in DNA replication and repair. FEN1 hydrolyses the phosphodiester bond one nucleotide into the duplex region of bifurcated double-flapped structures as found in lagging-strand DNA synthesis. These flap structures need to be...
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University of Sheffield
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.737874 |