Structural and biochemical investigation of the Sin3a:HDAC1:SDS3 transcriptional co-repressor complex

The Sin3a complex is a large multi-protein complex that is involved in embryonic development, cell cycle regulation, proliferation, oncogene regulation and senescence. The Sin3a protein acts as a scaffold protein and the complex contains several proteins including HDAC1 and HDAC2 as catalytic subuni...

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Bibliographic Details
Main Author: Nigi, Irene
Other Authors: Schwabe, John ; Cowley, Shaun
Published: University of Leicester 2018
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745901