Freeze-drying of engineered proteins using protein modelling tools and experimental validation
The development of therapeutic proteins is a driving force in the current manufacture of biopharmaceuticals. Freeze drying is widely used in the fabrication of final dosage forms of therapeutic proteins. Using a series of A33 Fab mutants, this thesis aimed to correlate their physicochemical properti...
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University College London (University of London)
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.746503 |