Hypophosphastasia (HPP): pathogenesis and current treatment options

Hypophosphatasia (HPP) is a rare, inherited, metabolic bone disease characterized by the abnormal development of bones and teeth, due to defective mineralization (1,2). HPP is caused by inactivating mutation(s) within the gene that encodes the tissue-nonspecific isozyme of alkaline phosphatase (TNSA...

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Bibliographic Details
Main Author: LaSalle, Luisa Ellis
Language:en_US
Published: 2018
Subjects:
HPP
Online Access:https://hdl.handle.net/2144/26886

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