Lipid biosynthesis in Ehrlich ascites tumor cells

• Main Author: Szabo, Elek Istvan
• Language: en_US
• Published: Boston University 2019
• Subjects: Ehrlich ascites carcinoma; Tumors; Lipid metabolism
• Online Access: https://hdl.handle.net/2144/34729

Thesis (Ph.D.)--Boston University === PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at [e-mail]. Thank you. === The present view of the lipid metabolism of tumors appears to be, as stated by Gore and Popjak (32) and Gore (11), that tumors in general lack the capacity to utilize acetate for the biosynthesis of lipids. The results of Medes et al. (12), Busch (13), and Busch and Baltrush (14), lend support to the view expressed by Gore and Popjak. However, evidence to the contrary, namely that the lipid metabolism in tumors is not impaired, also exists. In this regard the results of Trew and Begg (16), Jablonski and Olson (17), Olson et al. (54), and Haven (19,20) are of special significance. The lack of agreement in the results of various investigators was attributed by Henderson and LePage (15) to differences between the tumors studied, but it was felt that the discrepancies in the results could also be attributed to differences in the conditions of incubation, the importance of which was emphasized by Busch (27) [TRUNCATED]. === 2031-01-01