Molecular Modelling for Enzyme Inhibition: A Search for a New Treatment for Cataract and New Antimicrobials and Herbicides
There have been several reports that cataract development results from unregulated Ca2+ mediated degradation of lens crystallins. The calpain isoform m-calpain, a cysteine protease, is known to be a major player in cataract formation in rodent lenses and recent evidence indicates that over-activatio...
Main Author: | Stuart, Blair Gibb |
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Language: | en |
Published: |
University of Canterbury. Chemistry
2010
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Subjects: | |
Online Access: | http://hdl.handle.net/10092/4551 |
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