Clues of identification of protein-protein interaction sites.

Leung Ka-Kit. === Thesis submitted in: November 2004. === Thesis (M.Phil.)--Chinese University of Hong Kong, 2005. === Includes bibliographical references (leaves 67-71). === Abstracts in English and Chinese. === Abstract === Chapter CHAPTER 1. --- INTRODUCTION --- p.1 === Chapter 1.1 --- Backgroun...

Full description

Bibliographic Details
Other Authors: Leung, Ka-Kit.
Format: Others
Language:English
Chinese
Published: 2005
Subjects:
Online Access:http://library.cuhk.edu.hk/record=b5892544
http://repository.lib.cuhk.edu.hk/en/item/cuhk-325392
Description
Summary:Leung Ka-Kit. === Thesis submitted in: November 2004. === Thesis (M.Phil.)--Chinese University of Hong Kong, 2005. === Includes bibliographical references (leaves 67-71). === Abstracts in English and Chinese. === Abstract === Chapter CHAPTER 1. --- INTRODUCTION --- p.1 === Chapter 1.1 --- Background of protein structures --- p.1 === Chapter 1.2 --- Background of protein-protein interaction (PPI) --- p.4 === Chapter 1.2.1 --- Quaternary structure and protein complex --- p.4 === Chapter 1.2.2 --- Previous related work --- p.4 === Chapter 1.2.3 --- The kinetic and thermodynamic formalism --- p.6 === Chapter CHAPTER 2. --- MATERIALS AND METHODS --- p.10 === Chapter 2.1 --- Amino acid composition representative power modeling --- p.10 === Chapter 2.1.1 --- Propensity level modeling --- p.10 === Chapter 2.1.2 --- Polar atoms visualization --- p.17 === Chapter 2.2 --- Rigid structure representative power modeling --- p.17 === Chapter 2.3 --- Electrostatic potential modeling --- p.17 === Chapter 2.3.1 --- Charge residence --- p.17 === Chapter 2.3.2 --- Minimum Ribbon (MR) --- p.19 === Chapter 2.4 --- Examination of interface --- p.23 === Chapter 2.5 --- Identification procedures of a binding site --- p.24 === Chapter 2.6 --- System requirements --- p.24 === Chapter CHAPTER 3. --- RESULTS AND DISCUSSIONS --- p.24 === Chapter 3.1 --- Polar atoms --- p.25 === Chapter 3.2 --- Minimum Ribbon (MR) --- p.27 === Chapter 3.3 --- "Charge complementarity, propensity level and rigid structure orientation" --- p.31 === Chapter 3.4 --- Identification of interacting site --- p.36 === Chapter CHAPTER 4. --- CONCLUSIONS --- p.64 === System requirements --- p.65 === Basic operation --- p.65 === Limitation --- p.66