Highwire coordinates synapse formation and maturation by regulating both a map kinase cascade and the ability of the axon to respond to external cues in the giant fiber system of Drosophila Melanogaster
The ubiquitin ligase Highwire is responsible for cell-autonomously promoting synapse formation in the Drosophila Giant Fiber system. highwire mutants show defects in synaptic function and extra branching at the axon terminal, corresponding to transient branching that occur in the course of giant...
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| Format: | Others |
| Language: | English |
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Florida Atlantic University
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| Online Access: | http://purl.flvc.org/fau/fd/FA00004081 http://purl.flvc.org/fau/fd/FA00004081 |